

I have a PhD in this bullshit.


I have a PhD in this bullshit.


From what I remember from my neuroscience classes, TL;DR there are different networks that promote sleep vs wakefulness. Sleep involves firing of specific networks that are so in sync they generate brain waves that can be measured from the outside of your skull. Think delta waves. Alcohol has many non-specific targets in the brain that fuck up this rhythmic firing that keep you from entering REM and deep sleep.
The hypothalamus, a peanut-sized structure deep inside the brain, contains groups of nerve cells that act as control centers affecting sleep and wakefulness. Within the hypothalamus is the suprachiasmatic nucleus (SCN)—clusters of thousands of cells that receive information about light exposure directly from the eyes and control your behavioral rhythm. Some people with damage to the SCN sleep erratically throughout the day because they are not able to match their sleep/wake cycle (circadian rhythms) with the light-dark cycle. Most blind people maintain some ability to sense light to help them regulate their sleep/wake cycle.
The brainstem, which is made up of structures called the pons, medulla, and midbrain, controls the transitions between wake and sleep. Sleep-promoting cells within the hypothalamus and the brain stem produce a brain chemical called GABA, reduces activity in the hypothalamus and the brainstem. The brainstem (especially the pons and medulla) also plays a special role in REM sleep. It sends signals to relax muscles essential for body posture and limb movements, so that we don’t act out our dreams.
The thalamus sends and receives information from the senses to the cerebral cortex. The cerebral cortex is the covering of the brain that has many functions, including interpreting and processing short- and long-term memory. During most stages of sleep, the thalamus becomes quiet, letting you tune out the external world. But during REM sleep, the thalamus is active, sending the cortex images, sounds, and other sensations that fill our dreams.
The pineal gland, located within the brain’s two hemispheres, receives signals from the SCN and increases production of the hormone melatonin, which helps put you to sleep once the lights go down. Scientists believe that peaks and valleys of melatonin over time are important for matching the body’s circadian rhythm to the external cycle of light and darkness.
The basal forebrain, near the front and bottom of the brain, also promotes sleep and wakefulness, while part of the midbrain acts as a system to help us stay alert during the day. Release of a chemical called adenosine from cells helps make you feel sleepy. Caffeine counteracts sleepiness by blocking the actions of adenosine.
The amygdala, an almond-shaped structure involved in processing emotions, becomes increasingly active during REM sleep.
Alcohol has non specific targets in the brain. It reduces excitatory action through NMDA ligand gated ion channels. It enhances inhibitory action through GABA ligand gated ion channels. Fucking with those ion channels changes ions entering neurons which changes electrical signals that eventually propogate down the axon. Electrical signals in a nerve axon lead to the axon terminals releasing neurotransmitters to the next cell in the chain of the entire network. This fucks up the overall network/brain waves and fucks with your ability to enter deep sleep.
You can fall asleep faster with ethanol on board, but quality of sleep will be poor.
Nah, it was an antivaxer that got all butt hurt. You have a down vote too friend. Jokes on them, science doesn’t give a fuck about their feelings.
Corn can be fermented into burbon, so that tracks.


It’s a combination of vibe coding and absolutely no QA testing, because they fired a fuck ton of QA people 10 years ago. Microsoft is making it’s users beta test their fucking software through telemetry bug reporting. And we fucking pay for that privilege.
雪花飘飘 北风萧萧 天地一片苍茫 一剪寒梅 傲立雪中 只为伊人飘香 爱我所爱 无怨无悔 此情长留心间 雪花飘飘 北风萧萧 天地一片苍茫 一剪寒梅 傲立雪中 只为伊人飘香 爱我所爱 无怨无悔 此情长留心间
Snowflakes flutter, the north wind howls, The world is a vast expanse of white, A lone plum blossom stands proudly in the snow, Its fragrance is offered only for her. I love what I love, without regret, This love will forever remain in my heart. Snowflakes flutter, the north wind howls, The world is a vast expanse of white, A lone plum blossom stands proudly in the snow, Its fragrance is offered only for her. I love what I love, without regret, This love will forever remain in my heart.
Is this translation correct? If so, I don’t understand how this poetry is related; unless it’s all a metaphor that’s subtext for some kind of political message.


Remember Blizzard and diablo immortal, when they got booed during the reveal of the game, and then the devs were like, “does no one have phones?” Some of these CEOs and DEVS are so out of touch with what their customers want because they would rather huff their own farts all day, enjoying the smell of their own brand, instead of admit that they led product development to an area where there wasn’t market demand amongst their consumers.


Probably be less angry about grammar and spelling “nazis.” I’m guilty of those mistakes too, so I am not above being corrected myself.


Their, as in the disdain microsoft has for the user, not there, as in microsoft put the disdain in a box and it’s sitting across the room over there. However, your point is valid and stands.


Because they make so much more $ from selling your data. Microsoft would rather push these AI programs in an update, and bank on their users not noticing. The majority of users operate in a walled garden, they aren’t editing registry files or manually running commands, so they are less likely to notice the changes. It’s the power users that notice this shit, and sound the alarm.
Manure is also used as a fuel. Coal is too good for them.